Added: Jacinto Reisman - Date: 13.01.2022 00:34 - Views: 16226 - Clicks: 1793
This study compares the speed of onset of action of the extended release XR formulation of alprazolam with that of the compressed tablet CT formulation in a sample of outpatients with DSM-IV panic disorder. Diary records of hourly antianxiety benefit from a 9-week open label switch study of patients stabilized on alprazolam- CT for 3 weeks and then switched to an equivalent dose of alprazolam-XR, were used to examine the timing and magnitude of clinical benefit on both formulations.
The magnitude of benefit at the first hour after the first morning dose was similar for both formulations. Mean time to peak benefit was similar 1. Compared to the CT formulation, alprazolam-XR had a much longer duration of therapeutic action Thewhich may be related to the biotechnology and resultant pharmacokinetic profile of the XR preparation, suggest that alprazolam-XR has value as a "rescue" as well as a prophylactic or maintenance treatment in panic disorder. These must be viewed in the context of the study limitations including its small size, the lack of independence of groups in a switch study, and the limitations of the diary records used.
Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Display options Display options. Create file Cancel. citation Subject: 1 selected item: - PubMed. Format: Summary Summary text Abstract Abstract text. MeSH and other data. Send Cancel. Add to Collections Create a new collection Add to Xanax duration of action existing collection. Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again.
Add Cancel. Add to My Bibliography My Bibliography. Unable to load your delegates due to an error Please try again. Your saved search Name of saved search:. Search terms:. Test search terms. Would you like updates of new search ? : change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items.
Send even when there aren't any new. Optional text in :. Save Cancel. Create a file for external citation management software Create file Cancel. of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Cite Display options Display options.
Abstract This study compares the speed of onset of action of the extended release XR formulation of alprazolam with that of the compressed tablet CT formulation in a sample of outpatients with DSM-IV panic disorder. Similar articles Method for assessing the duration of therapeutic Xanax duration of action and milligram equivalence of anxiolytics. Sheehan DV, et al. PMID: No abstract available.
A double-blind, placebo-controlled, multicenter study with alprazolam and extended-release alprazolam in the treatment of panic disorder. Pecknold J, et al. J Clin Psychopharmacol. Pharmacokinetics of an extended release formulation of alprazolam Xanax XR in healthy normal adolescent and adult volunteers.
Glue P, et al. Am J Ther. Actas Esp Psiquiatr. PMID: Review. Efficacy studies of alprazolam in panic disorder. Spiegel DA. Psychopharmacol Bull. See all similar articles. Cited by 1 article Treating comorbid anxiety and depression: Psychosocial and pharmacological approaches. Coplan JD, et al. World J Psychiatry. Publication types Comparative Study Actions. Randomized Controlled Trial Actions. Research Support, Non-U. Gov't Actions. MeSH terms Adult Actions. Biological Availability Actions. Cross-Over Studies Actions. Delayed-Action Preparations Actions. Dose-Response Relationship, Drug Actions.
Drug Administration Schedule Actions. Female Actions. Humans Actions. Male Actions. Medical Records Actions. Middle Aged Actions. Patient Satisfaction Actions. Tablets Actions. Substances Anti-Anxiety Agents Actions. Alprazolam Actions. Copy Download.Xanax duration of action
email: [email protected] - phone:(258) 545-9536 x 5453
How long does Xanax last?